Direct evidence for involvement of NF-kappaB in transcriptional activation of tumor necrosis factor by a spirochetal lipoprotein.

Variable major lipoprotein (Vmp) is a major tumor necrosis factor (TNF)-inducing component of Borrelia recurrentis, the agent of louse-borne relapsing fever. B. recurrentis Vmp rapidly stimulates nuclear translocation of NF-kappaB and proinflammatory cytokine gene expression in the human monocyte-li...

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Bibliografiske detaljer
Main Authors: Udalova, I, Vidal, V, Scragg, I, Kwiatkowski, D
Format: Journal article
Sprog:English
Udgivet: 2000