Ligand binding to a G protein-coupled receptor captured in a mass spectrometer.

G protein (heterotrimeric guanine nucleotide-binding protein)-coupled receptors belong to the largest family of membrane-embedded cell surface proteins and are involved in a diverse array of physiological processes. Despite progress in the mass spectrometry of membrane protein complexes, G protein-c...

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Bibliographic Details
Main Authors: Yen, H, Hopper, J, Liko, I, Allison, T, Zhu, Y, Wang, D, Stegmann, M, Mohammed, S, Wu, B, Robinson, C
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2017