Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic

Genome editing using clustered regularly interspersed short palindromic repeats (CRISPR) and CRISPR-associated proteins offers the potential to facilitate safe and effective treatment of genetic diseases refractory to other types of intervention. Here, we identify some of the major challenges for cl...

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Bibliographic Details
Main Authors:	Nicol, D, Eckstein, L, Morrison, M, Sherkow, J, Otlowski, M, Whitton, T, Bubela, T, Burdon, K, Chalmers, D, Chan, S, Charlesworth, J, Critchley, C, Crossley, M, de Lacey, S, Dickinson, J, Hewitt, A, Kamens, J, Kato, K, Kleiderman, E, Kodama, S, Liddicoat, J, Mackey, D, Newson, A, Nielsen, J, Wagner, J, McWhirter, R
Format:	Journal article
Language:	English
Published:	BioMed Central 2017

Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic

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