Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic
Genome editing using clustered regularly interspersed short palindromic repeats (CRISPR) and CRISPR-associated proteins offers the potential to facilitate safe and effective treatment of genetic diseases refractory to other types of intervention. Here, we identify some of the major challenges for cl...
Main Authors: | Nicol, D, Eckstein, L, Morrison, M, Sherkow, J, Otlowski, M, Whitton, T, Bubela, T, Burdon, K, Chalmers, D, Chan, S, Charlesworth, J, Critchley, C, Crossley, M, de Lacey, S, Dickinson, J, Hewitt, A, Kamens, J, Kato, K, Kleiderman, E, Kodama, S, Liddicoat, J, Mackey, D, Newson, A, Nielsen, J, Wagner, J, McWhirter, R |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2017
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