Time dependent asymptotic analysis of the gene regulatory network of the AcrAB-TolC efflux pump system in gram-negative bacteria

Efflux pumps are a mechanism of intrinsic and evolved resistance in bacteria. If an efflux pump can expel an antibiotic so that its concentration within the cell is below a killing threshold the bacteria are resistant to the antibiotic. Efflux pumps may be specific or they may pump various different...

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Bibliographic Details
Main Authors: Youlden, GH, Ricci, V, Wang-Kan, X, Piddock, LJV, Jabbari, S, King, JR
Format: Journal article
Language:English
Published: Springer 2021