A comparative study of Lrrk2 function in primary neuronal cultures.

OBJECTIVE: To assess the contribution of wild-type, mutant and loss of leucine-rich repeat kinase-2 (LRRK2; Lrrk2) on dendritic neuronal arborization. BACKGROUND: LRRK2 mutations are recognized as the major genetic determinant of susceptibility to Parkinson's disease for which a cellular assay...

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Bibliographic Details
Main Authors: Dächsel, J, Behrouz, B, Yue, M, Beevers, J, Melrose, H, Farrer, M
Format: Journal article
Language:English
Published: 2010