Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin.

Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin.

The mode of binding of oligosaccharides to griffithsin, an antiviral lectin from the red alga Griffithsia sp., was investigated by a combination of X-ray crystallography, isothermal titration calorimetry, and molecular modeling. The structures of complexes of griffithsin with 1-->6alpha-manno...

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Bibliografiske detaljer
Main Authors:	Ziółkowska, N, Shenoy, SR, O'Keefe, B, McMahon, J, Palmer, K, Dwek, R, Wormald, M, Wlodawer, A
Format:	Journal article
Sprog:	English
Udgivet:	2007

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