Oxidative DNA cleavage with clip‐phenanthroline triplex‐forming oligonucleotide hybrids

A systematic study of several new types of hybrids of Cu‐chelated clamped phenanthroline artificial metallonuclease (AMN) with triplex‐forming oligonucleotides (TFO) for sequence‐specific cleavage of double‐stranded DNA (dsDNA) is reported. The synthesis of these AMN–TFO hybrids is based on applicat...

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Bibliographic Details
Main Authors: Panattoni, A, El-Sagheer, AH, Brown, T, Kellett, A, Hocek, M
Format: Journal article
Language:English
Published: Wiley 2019