Modulating microtubule stability enhances the cytotoxic response of cancer cells to Paclitaxel.

The extracellular matrix protein TGFBI enhances the cytotoxic response of cancer cells to paclitaxel by affecting integrin signals that stabilize microtubules. Extending the implications of this knowledge, we tested the more general hypothesis that cancer cell signals which increase microtubule stab...

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Bibliographic Details
Main Authors: Ahmed, A, Wang, X, Lu, Z, Goldsmith, J, Le, X, Grandjean, G, Bartholomeusz, G, Broom, B, Bast, R
Format: Journal article
Language:English
Published: 2011