Mitochondrial genes are altered in blood early in Alzheimer's disease

Although mitochondrial dysfunction is a consistent feature of Alzheimer's disease (AD) in the brain and blood, the molecular mechanisms behind these phenomena are unknown. Here we have replicated our previous findings demonstrating reduced expression of nuclear-encoded oxidative phosphorylation...

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Bibliographic Details
Main Authors: Lunnon, K, Keohan, A, Pidsley, R, Newhouse, S, Riddoch-Contreras, J, Thubron, E, Devall, M, Soininen, H, Kłoszewsk, I, Mecocci, P, Tsolaki, M, Vellas, B, Schalkwyk, L, Dobson, R, Malik, A, Powell, J, Lovestone, S, Hodges, A
Format: Journal article
Published: Elsevier 2017