The NK1 receptor antagonist N-acetyl-l-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model
Background: Dyskinesia or abnormal involuntary movements (AIMs) are a disabling effect of chronic l-DOPA administration and consequent pulsatile stimulation of dopamine receptors. This abnormal activation causes maladaptive changes including upregulation of FosB expression in dynorphin containing st...
Príomhchruthaitheoirí: | Thornton, E, Hassall, M, Corrigan, F, Vink, R |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
Elsevier
2014
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Míreanna comhchosúla
Míreanna comhchosúla
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