Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer.

BACKGROUND: Ulcerative colitis associated colorectal cancer (UCACRC) has several distinctive clinicopathological and genetic features which differ from sporadic colorectal cancer (SCRC). Hypermethylation of the E-cadherin gene (CDH1) has not been described previously in colorectal cancer. AIMS: A pa...

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Bibliographic Details
Main Authors: Wheeler, J, Kim, H, Efstathiou, J, Ilyas, M, Mortensen, N, Bodmer, W
Format: Journal article
Language:English
Published: 2001