Activation of the non-canonical inflammasome in mouse and human cells

The non-canonical inflammasome is a signaling platform that allows for the detection of cytoplasmic lipopolysaccharides (LPS) in immune and non-immune cells. Upon detection of LPS, this inflammasome activates the signaling proteases caspase-4 and -5 (in humans) and caspase-11 (in mice). Inflammatory...

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Bibliographic Details
Main Authors: Bezbradica, JS, Coll, RC, Boucher, D
Other Authors: Abdul-Sater, AA
Format: Book section
Language:English
Published: Humana Press 2022