EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis

<p style="text-align:justify;"> <b>Background:</b> Ephrin receptor B2 (EPHB2) has recently been proposed as a novel tumor suppressor gene in colorectal cancer (CRC). Inactivation of the gene has been shown to correlate with progression of colorectal tumorigenesis, and so...

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Main Authors: Kokko, A, Laiho, P, Lehtonen, R, Korja, S, Carvajal-Carmona, L, Järvinen, H, Mecklin, J, Eng, C, Schleutker, J, Tomlinson, I, Vahteristo, P, Aaltonen, L
Format: Journal article
Language:English
Published: BioMed Central 2006