Shear stress insensitivity of endothelial nitric oxide synthase expression as a genetic risk factor for coronary heart disease.

Coronary heart disease (CHD) is based on the development of atherosclerosis in coronary arteries. Shear stress-induced endothelial nitric oxide (NO) release not only contributes to local blood pressure control but also effectively helps to retard atherosclerosis. Therefore, functionally relevant pol...

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Bibliographic Details
Main Authors: Cattaruzza, M, Guzik, T, Słodowski, W, Pelvan, A, Becker, J, Halle, M, Buchwald, AB, Channon, K, Hecker, M
Format: Journal article
Language:English
Published: 2004