Shear stress insensitivity of endothelial nitric oxide synthase expression as a genetic risk factor for coronary heart disease.
Coronary heart disease (CHD) is based on the development of atherosclerosis in coronary arteries. Shear stress-induced endothelial nitric oxide (NO) release not only contributes to local blood pressure control but also effectively helps to retard atherosclerosis. Therefore, functionally relevant pol...
Main Authors: | , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2004
|