Depletion of the type 1 IGF receptor delays repair of radiation-induced DNA double strand breaks

<h4>Background and purpose:</h4> <p>IGF-1R depletion sensitizes prostate cancer cells to ionizing radiation and DNAdamaging cytotoxic drugs. This study investigated the hypothesis that IGF-1R regulates DNA double strand break (DSB) repair.</p> <h4>Methods:</h4> &l...

Full description

Bibliographic Details
Main Authors: Turney, B, Kerr, M, Chitnis, M, Lodhia, K, Wang, Y, Riedemann, J, Rochester, M, Protheroe, A, Brewster, S, Macaulay, V
Format: Journal article
Language:English
Published: Elsevier 2012