Recipient memory-like lymphocytes remain unresponsive to graft antigens after CAMPATH-1H induction with reduced maintenance immunosuppression.

BACKGROUND: Treatment with CAMPATH-1H at the time of transplantation allows reduced maintenance immunosuppression. We hypothesized that CAMPATH-1H induction would modulate the response of repopulating leukocytes to donor alloantigens. METHODS: The phenotype, proliferative and stimulatory capacity o...

Full description

Bibliographic Details
Main Authors: Trzonkowski, P, Zilvetti, M, Friend, P, Wood, K
Format: Journal article
Language:English
Published: 2006