Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen/paracetamol combinations after third molar extraction

We defined response in acute pain trials to percentage of maximum possible efficacy. Minimum efficacy criteria (MEC) of 0%, or at least 15%, 30%, 50%, and 70% pain relief were used to examine stability over time using total pain relief and summed pain intensity difference (SPID), sex differences, an...

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Bibliographic Details
Main Authors: Moore, R, Straube, S, Paine, J, Derry, S, McQuay, H
Other Authors: International Association for the Study of PainOxford Pain Relief Trust
Format: Journal article
Language:English
Published: Elsevier 2011
Subjects: