Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen/paracetamol combinations after third molar extraction
We defined response in acute pain trials to percentage of maximum possible efficacy. Minimum efficacy criteria (MEC) of 0%, or at least 15%, 30%, 50%, and 70% pain relief were used to examine stability over time using total pain relief and summed pain intensity difference (SPID), sex differences, an...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2011
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