Real-time monitoring of enzymatic DNA hydrolysis by electrospray ionization mass spectrometry

A fast and direct method for the monitoring of enzymatic DNA hydrolysis was developed using electrospray ionization mass spectrometry. We incorporated the use of a robotic chip-based electrospray ionization source for increased reproducibility and throughput. The mass spectrometry method allows the...

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Bibliographic Details
Main Authors: van den Heuvel, R, Gato, S, Versluis, C, Gerbaux, P, Kleanthous, K, Heck, A
Format: Journal article
Language:English
Published: 2005