Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.

عرض إصدارات أخرى (1)

Dual-specificity tyrosine-(Y)-phosphorylation-regulated kinases (DYRKs) play key roles in brain development, regulation of splicing, and apoptosis, and are potential drug targets for neurodegenerative diseases and cancer. We present crystal structures of one representative member of each DYRK subfam...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Soundararajan, M, Roos, A, Savitsky, P, Filippakopoulos, P, Kettenbach, A, Olsen, J, Gerber, SA, Eswaran, J, Knapp, S, Elkins, J
التنسيق:	Journal article
اللغة:	English
منشور في:	2013

مواد مشابهة

Structures of down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition
حسب: Soundararajan, M, وآخرون
منشور في: (2013)

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