DNA as an important target in radiation-induced apoptosis of MYC and MYC plus RAS transfected rat embryo fibroblasts.

DNA as an important target in radiation-induced apoptosis of MYC and MYC plus RAS transfected rat embryo fibroblasts.

PURPOSE: This study uses a radiation chemistry approach to determine if DNA is an important target for radiation-induced apoptosis of myc (MR4) and myc plus ras (3.7) transfected rat embryo fibroblast cell lines. MATERIALS AND METHODS: The radiation protection efficiency of four thiols was compared...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Ayene, I, Bernhard, E, Mckenna, W, Muschel, R, Krisch, R, Koch, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2000

Eitemau Tebyg

C-Raf-1 protein kinase is not essential for Ras transformation of mouse embryo fibroblasts.
gan: Gupta, A, et al.
Cyhoeddwyd: (2003)

The Ras radiation resistance pathway.
gan: Gupta, A, et al.
Cyhoeddwyd: (2001)

The RAS signal transduction pathway and its role in radiation sensitivity.
gan: Mckenna, W, et al.
Cyhoeddwyd: (2003)

Multiple phenotypes associated with Myc-induced transformation of chick embryo fibroblasts can be dissociated by a basic region mutation.
gan: Crouch, D, et al.
Cyhoeddwyd: (1996)

MYC Immunohistochemistry Predicts MYC Rearrangements by FISH
gan: Julum Nwanze, et al.
Cyhoeddwyd: (2017-09-01)

Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignancies
gan: Daniel F. Liefwalker, et al.
Cyhoeddwyd: (2021-08-01)

MYC sensitises cells to apoptosis by driving energetic demand
gan: Joy Edwards-Hicks, et al.
Cyhoeddwyd: (2022-08-01)

MYC prevents apoptosis and enhances endoreduplication induced by paclitaxel.
gan: Giuliana Gatti, et al.
Cyhoeddwyd: (2009-01-01)

Temporal Requirements of cMyc Protein for Reprogramming Mouse Fibroblasts
gan: Corey Heffernan, et al.
Cyhoeddwyd: (2012-01-01)

c-Myc alone is enough to reprogram fibroblasts into functional macrophages
gan: Shanshan Li, et al.
Cyhoeddwyd: (2024-09-01)

Induction of Pluripotency in Adult Equine Fibroblasts without c-MYC
gan: Khodadad Khodadadi, et al.
Cyhoeddwyd: (2012-01-01)

Transfection of Sponge Cells and Intracellular Localization of Cancer-Related MYC, RRAS2, and DRG1 Proteins
gan: Kristina Dominko, et al.
Cyhoeddwyd: (2023-02-01)

Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas.
gan: Phuoc T Tran, et al.
Cyhoeddwyd: (2008-05-01)

Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development.
gan: Zi-Qiang Zhou, et al.
Cyhoeddwyd: (2011-01-01)

Tuning the MYC response
gan: Ying Zheng, et al.
Cyhoeddwyd: (2016-07-01)

K-RAS point mutation, and amplification of C-MYC and C-ERBB2 in colon adenocarcinoma.
gan: Tadeusz Pawełczyk, et al.
Cyhoeddwyd: (2004-10-01)

TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding.
gan: Tian-Yeh Lim, et al.
Cyhoeddwyd: (2023-03-01)

MYC overexpression leads to increased chromatin interactions at superenhancers and MYC binding sites
gan: See, Yi Xiang, et al.
Cyhoeddwyd: (2022)

MYC: there is more to it than cancer
gan: Mariano F. Zacarías-Fluck, et al.
Cyhoeddwyd: (2024-03-01)

BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming
gan: Esther J.Y. Kim, et al.
Cyhoeddwyd: (2018-02-01)

Ras inhibitors and radiation therapy.
gan: Jones, H, et al.
Cyhoeddwyd: (2001)

RAS-Mediated radiation resistance is not linked to MAP kinase activation in two bladder carcinoma cell lines.
gan: Gupta, A, et al.
Cyhoeddwyd: (2000)

MYC overexpression in cancer increases chromatin interactions at superenhancers and c-Myc binding sites
gan: See, Yi Xiang
Cyhoeddwyd: (2022)

Review: proteins c-Myc and Myc-nick as potential targets for the melignant melanoma treatment
gan: G. Maryniuk, et al.
Cyhoeddwyd: (2023-07-01)

Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution
gan: Nicole M. Sodir, et al.
Cyhoeddwyd: (2022-11-01)

Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc
gan: Sarah K. Madden, et al.
Cyhoeddwyd: (2021-01-01)

Regulation of α-Ketoglutarate levels by Myc affects metabolism and demethylation in porcine early embryos
gan: Ran Ding, et al.
Cyhoeddwyd: (2024-11-01)

Ras regulation of radioresistance in cell culture.
gan: Gupta, A, et al.
Cyhoeddwyd: (2001)

Alternative <i>c-MYC</i> mRNA Transcripts as an Additional Tool for c-Myc2 and c-MycS Production in BL60 Tumors
gan: Dina Ibrahim, et al.
Cyhoeddwyd: (2022-06-01)

Direct evidence for the contribution of activated N-ras and K-ras oncogenes to increased intrinsic radiation resistance in human tumor cell lines.
gan: Bernhard, E, et al.
Cyhoeddwyd: (2000)

Radiation sensitization by inhibition of activated Ras.
gan: Brunner, T, et al.
Cyhoeddwyd: (2004)

High Intrinsic Oncogenic Potential in the Myc-Box-Deficient <i>Hydra</i> Myc3 Protein
gan: Marion Lechable, et al.
Cyhoeddwyd: (2023-04-01)

Cohesin is required for activation of MYC by estradiol.
gan: Miranda V McEwan, et al.
Cyhoeddwyd: (2012-01-01)

HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes
gan: Aleksandra Boikova, et al.
Cyhoeddwyd: (2022-10-01)

Manipulating Myc for reparative regeneration
gan: Camilla Ascanelli, et al.
Cyhoeddwyd: (2024-03-01)

Regulation of Nucleolar Activity by MYC
gan: Isabella N. Brown, et al.
Cyhoeddwyd: (2022-02-01)

The Myc Road to Hearing Restoration
gan: Bernd Fritzsch, et al.
Cyhoeddwyd: (2012-09-01)

Getting to grips with c-Myc
gan: Dirk Eick
Cyhoeddwyd: (2018-01-01)

Targeting c-MYC with T-cells.
gan: Florian Helm, et al.
Cyhoeddwyd: (2013-01-01)

Dissecting transcriptional amplification by MYC
gan: Zuqin Nie, et al.
Cyhoeddwyd: (2020-07-01)