Cellular confocal fluorescence studies and cytotoxic activity of new Zn(II) bis(thiosemicarbazonato) complexes.

We report the synthesis and characterisation of new, highly fluorescent, zinc complexes of bis(thiosemicarbazone) ligands incorporating extended aromatic backbones which are cytotoxic at levels comparable to cisplatin; cellular fluorescence imaging studies suggest these cause cell death by disruptio...

Full description

Bibliographic Details
Main Authors: Pascu, S, Waghorn, P, Conry, T, Lin, B, Betts, H, Dilworth, JR, Sim, R, Churchill, G, Aigbirhio, F, Warren, J
Format: Journal article
Language:English
Published: 2008