Cellular confocal fluorescence studies and cytotoxic activity of new Zn(II) bis(thiosemicarbazonato) complexes.
We report the synthesis and characterisation of new, highly fluorescent, zinc complexes of bis(thiosemicarbazone) ligands incorporating extended aromatic backbones which are cytotoxic at levels comparable to cisplatin; cellular fluorescence imaging studies suggest these cause cell death by disruptio...
Main Authors: | Pascu, S, Waghorn, P, Conry, T, Lin, B, Betts, H, Dilworth, JR, Sim, R, Churchill, G, Aigbirhio, F, Warren, J |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2008
|
Similar Items
-
Synthesis, radiolabelling and confocal fluorescence microscopy of styrene-derivatised bis(thiosemicarbazonato)zinc and -copper complexes
by: Holland, J, et al.
Published: (2008) -
Synthesis, radiolabelling and confocal fluorescence microscopy of styrene-derivatised bis(thiosemicarbazonato)zinc and -copper complexes
by: Holland, J, et al.
Published: (2008) -
Designing Zn(II) and Cu(II) derivatives as probes for in vitro fluorescence imaging.
by: Pascu, S, et al.
Published: (2007) -
FLUORESCENT COPPER(II) BIS(THIOSEMICARBAZONATES): FROM SYNTHESIS TO RADIOLABELLING, IN VITRO CYTOTOXICITY AND CONFOCAL FLUORESCENCE MICROSCOPY
by: Pascu, S, et al.
Published: (2010) -
Fluorescent copper(II) bis(thiosemicarbazonates): synthesis, structures, electron paramagnetic resonance, radiolabeling, in vitro cytotoxicity and confocal fluorescence microscopy studies.
by: Pascu, S, et al.
Published: (2010)