Matrix metalloproteinase 9 promoter activity is induced coincident with invasion during tumor progression.

Matrix metalloproteinase 9 (MMP-9, also known as gelatinase B or 92-kd Type IV collagenase) is overexpressed in many human and murine cancers. We induced carcinomas in mice carrying a transgene that links the MMP-9 promoter to the reporter ss-galactosidase so that activation of the MMP-9 promoter wo...

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Bibliographic Details
Main Authors: Kupferman, M, Fini, M, Muller, W, Weber, R, Cheng, Y, Muschel, R
Format: Journal article
Language:English
Published: 2000