Matrix metalloproteinase 9 promoter activity is induced coincident with invasion during tumor progression.
Matrix metalloproteinase 9 (MMP-9, also known as gelatinase B or 92-kd Type IV collagenase) is overexpressed in many human and murine cancers. We induced carcinomas in mice carrying a transgene that links the MMP-9 promoter to the reporter ss-galactosidase so that activation of the MMP-9 promoter wo...
Main Authors: | Kupferman, M, Fini, M, Muller, W, Weber, R, Cheng, Y, Muschel, R |
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Format: | Journal article |
Language: | English |
Published: |
2000
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