GPC3-Unc5 receptor complex structure and role in cell migration

GPC3-Unc5 receptor complex structure and role in cell migration

Neural migration is a critical step during brain development that requires the interactions of cell-surface guidance receptors. Cancer cells often hijack these mechanisms to disseminate. Here, we reveal crystal structures of Uncoordinated-5 receptor D (Unc5D) in complex with morphogen receptor glypi...

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Bibliographic Details
Main Authors: Akkermans, O, Delloye-Bourgeois, C, Peregrina, C, Carrasquero-Ordaz, M, Kokolaki, M, Berbeira-Santana, M, Chavent, M, Reynaud, F, Raj, R, Agirre, J, Aksu, M, White, ES, Lowe, E, Ben Amar, D, Zaballa, S, Huo, J, Pakos, I, McCubbin, PTN, Comoletti, D, Owens, RJ, Robinson, CV, Castellani, V, del Toro, D, Seiradake, E
Format: Journal article
Language:English
Published: Cell Press 2022

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