Interdomain conformational changes provide allosteric regulation en route to chorismate
Multifunctional proteins play a variety of roles in metabolism. Here we examine the catalytic function of the combined 3-deoxy-D-arabino heptulosonate 7-phosphate synthase (DAH7PS) and chorismate mutase (CM) from Geobacillus sp. DAH7PS operates at the start of the biosynthetic pathway for aromatic m...
Main Authors: | , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology
2016
|