Modelling and simulation of phenotypic variability in cardiac tissue and application to stem cell-derived cardiomyocytes

<p>Prediction of the safety of a novel pharmaceutical compound at the earliest possible stage of development is of great importance for drug discovery. Cardiac side-effects are a particular cause for concern, with several drugs such as Terfenadine and Cisapride having being withdrawn from the...

Full description

Bibliographic Details
Main Author: Bowler, L
Other Authors: Mirams, G
Format: Thesis
Language:English
Published: 2018
Subjects: