Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells.

The cytokines controlling the development of human interleukin (IL) 17--producing T helper cells in vitro have been difficult to identify. We addressed the question of the development of human IL-17--producing T helper cells in vivo by quantifying the production and secretion of IL-17 by fresh T cel...

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Bibliographic Details
Main Authors: de Beaucoudrey, L, Puel, A, Filipe-Santos, O, Cobat, A, Ghandil, P, Chrabieh, M, Feinberg, J, von Bernuth, H, Samarina, A, Jannière, L, Fieschi, C, Stéphan, J, Boileau, C, Lyonnet, S, Jondeau, G, Cormier-Daire, V, Le Merrer, M, Hoarau, C, Lebranchu, Y, Lortholary, O, Chandesris, M, Tron, F, Gambineri, E, Bianchi, L, Rodriguez-Gallego, C
Format: Journal article
Language:English
Published: 2008