Bromodomains as therapeutic targets.
Acetylation of lysine residues is a post-translational modification with broad relevance to cellular signalling and disease biology. Enzymes that 'write' (histone acetyltransferases, HATs) and 'erase' (histone deacetylases, HDACs) acetylation sites are an area of extensive resear...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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