Nanoscale ligand spacing influences receptor triggering in T cells and NK cells.

Bioactive nanoscale arrays were constructed to ligate activating cell surface receptors on T cells (the CD3 component of the TCR complex) and natural killer (NK) cells (CD16). These arrays are formed from biofunctionalized gold nanospheres with controlled interparticle spacing in the range 25-104 nm...

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Bibliographic Details
Main Authors: Delcassian, D, Depoil, D, Rudnicka, D, Liu, M, Davis, D, Dustin, M, Dunlop, I
Format: Journal article
Language:English
Published: 2013