Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

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Obstacles to developing an HIV-1 vaccine include extensive viral diversity and lack of correlates of protective immunity. High mutation rates allow HIV-1 to adapt rapidly to selective forces such as antiretroviral therapy and immune pressure, including HIV-1-specific CTLs that select viral variants...

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Huvudupphovsmän: Dong, T, Zhang, Y, Xu, K, Yan, H, James, I, Peng, Y, Blais, M, Gaudieri, S, Chen, X, Lun, W, Wu, H, Qu, W, Rostron, T, Li, N, Mao, Y, Mallal, S, Xu, X, McMichael, A, John, M, Rowland-Jones, S
Materialtyp: Journal article
Språk:English
Publicerad: 2011

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