Attenuation of influenza A virus mRNA levels by promoter mutations.

Attenuation of influenza A virus mRNA levels by promoter mutations.

We have engineered influenza A/WSN/33 viruses which have viral RNA (vRNA) segments with altered base pairs in the conserved double-stranded region of their vRNA promoters. The mutations were introduced into the segment coding for the neuraminidase (NA) by using a reverse genetics system. Two of the...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Fodor, E, Palese, P, Brownlee, G, García-Sastre, A
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	1998

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