Altered peptide ligands narrow the repertoire of cellular immune responses by interfering with T-cell priming.

Variation in epitopes of infectious pathogens inhibits various effector functions of T lymphocytes through antagonism of the T-cell receptor. However, a more powerful strategy for immune evasion would be to prevent the induction of T-cell responses. We report here mutual 'interference' wit...

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Bibliographic Details
Main Authors: Plebanski, M, Lee, E, Hannan, C, Flanagan, K, Gilbert, S, Gravenor, M, Hill, A
Format: Journal article
Language:English
Published: 1999