Structural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3.

The toxin colicin E3 targets the 30S subunit of bacterial ribosomes and cleaves a phosphodiester bond in the decoding center. We present the crystal structure of the 70S ribosome in complex with the cytotoxic domain of colicin E3 (E3-rRNase). The structure reveals how the rRNase domain of colicin bi...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Ng, C, Lang, K, Meenan, N, Sharma, A, Kelley, A, Kleanthous, K, Ramakrishnan, V
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2010