Structural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3.

Structural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3.

The toxin colicin E3 targets the 30S subunit of bacterial ribosomes and cleaves a phosphodiester bond in the decoding center. We present the crystal structure of the 70S ribosome in complex with the cytotoxic domain of colicin E3 (E3-rRNase). The structure reveals how the rRNase domain of colicin bi...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Ng, C, Lang, K, Meenan, N, Sharma, A, Kelley, A, Kleanthous, K, Ramakrishnan, V
التنسيق:	Journal article
اللغة:	English
منشور في:	2010

مواد مشابهة

Colicin E3 cleavage of 16S rRNA impairs decoding and accelerates tRNA translocation on Escherichia coli ribosomes.
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