Structural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3.
The toxin colicin E3 targets the 30S subunit of bacterial ribosomes and cleaves a phosphodiester bond in the decoding center. We present the crystal structure of the 70S ribosome in complex with the cytotoxic domain of colicin E3 (E3-rRNase). The structure reveals how the rRNase domain of colicin bi...
Κύριοι συγγραφείς: | Ng, C, Lang, K, Meenan, N, Sharma, A, Kelley, A, Kleanthous, K, Ramakrishnan, V |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2010
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Colicin E3 cleavage of 16S rRNA impairs decoding and accelerates tRNA translocation on Escherichia coli ribosomes.
ανά: Lancaster, L, κ.ά.
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Experimental and computational analyses of the energetic basis for dual recognition of immunity proteins by colicin endonucleases.
ανά: Keeble, A, κ.ά.
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Colicins exploit native disorder to gain cell entry: a hitchhiker's guide to translocation.
ανά: Bonsor, D, κ.ά.
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The kinetic basis for dual recognition in colicin endonuclease-immunity protein complexes.
ανά: Keeble, A, κ.ά.
Έκδοση: (2005) -
Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3.
ανά: Walker, D, κ.ά.
Έκδοση: (2004)