Incidence of serum anti-P/O-type and anti-N-type calcium channel autoantibodies in the Lambert-Eaton myasthenic syndrome.

The Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease in which autoantibodies are directed against voltage-gated calcium channels (VGCCs) at presynaptic nerve terminals. We first demonstrated the presence of P/Q-type and N-type VGCCs in digitonin extracts prepared from human and rabb...

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Bibliographic Details
Main Authors: Motomura, M, Lang, B, Johnston, I, Palace, J, Vincent, A, Newsom-Davis, J
Format: Journal article
Language:English
Published: 1997