Polygenic prediction of occupational status GWAS elucidates genetic and environmental interplay in intergenerational transmission, careers and health in UK Biobank

Socioeconomic status (SES) impacts health and life-course outcomes. This genome-wide association study (GWAS) of sociologically informed occupational status measures (ISEI, SIOPS, CAMSIS) using the UK Biobank (N = 273,157) identified 106 independent single-nucleotide polymorphisms of which 8 are nov...

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Detalhes bibliográficos
Principais autores: Akimova, ET, Wolfram, T, Ding, X, Tropf, FC, Mills, MC
Formato: Journal article
Idioma:English
Publicado em: Nature Research 2024