Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders.

By impairing both function and survival, the severe reduction in oxygen availability associated with high-altitude environments is likely to act as an agent of natural selection. We used genomic and candidate gene approaches to search for evidence of such genetic selection. First, a genome-wide alle...

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Bibliographic Details
Main Authors:	Beall, C, Cavalleri, G, Deng, L, Elston, R, Gao, Y, Knight, J, Li, C, Li, J, Liang, Y, McCormack, M, Montgomery, H, Pan, H, Robbins, P, Shianna, K, Tam, S, Tsering, N, Veeramah, K, Wang, W, Wangdui, P, Weale, M, Xu, Y, Xu, Z, Yang, L, Zaman, M, Zeng, C
Format:	Journal article
Language:	English
Published:	2010

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders.

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