Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders.
By impairing both function and survival, the severe reduction in oxygen availability associated with high-altitude environments is likely to act as an agent of natural selection. We used genomic and candidate gene approaches to search for evidence of such genetic selection. First, a genome-wide alle...
Päätekijät: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
2010
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