The N-terminal region of the PA subunit of the RNA polymerase of influenza A/HongKong/156/97 (H5N1) influences promoter binding.

BACKGROUND: The RNA polymerase of influenza virus is a heterotrimeric complex of PB1, PB2 and PA subunits which cooperate in the transcription and replication of the viral genome. Previous research has shown that the N-terminal region of the PA subunit of influenza A/WSN/33 (H1N1) virus is involved...

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Detalles Bibliográficos
Main Authors: Kashiwagi, T, Leung, B, Deng, T, Chen, H, Brownlee, G
Formato: Journal article
Idioma:English
Publicado: Public Library of Science 2009