Preparing the "soil": the primary tumor induces vasculature reorganization in the sentinel lymph node before the arrival of metastatic cancer cells.

Sentinel lymph node (SLN) metastasis is the first step in the spreading of cancer in many malignancies. Tumor-reactive lymphadenopathy in SLNs has been observed for decades, but alterations of the lymphatic channels and vasculature in these nodes before the arrival of metastatic tumor cells remain u...

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Bibliographic Details
Main Authors: Qian, C, Berghuis, B, Tsarfaty, G, Bruch, M, Kort, E, Ditlev, J, Tsarfaty, I, Hudson, E, Jackson, D, Petillo, D, Chen, J, Resau, J, Teh, B
Format: Journal article
Language:English
Published: 2006