Methotrexate is an alternative to azathioprine in neuromyelitis optica spectrum disorders with aquaporin-4 antibodies.

BACKGROUND: Neuromyelitis optica (NMO) is a severe autoimmune inflammatory disorder associated with considerable relapse-related disability. Immunosuppression is the mainstay of treatment but many patients do not tolerate first-line immunosuppressive agents, or experience ongoing relapses. OBJECTIV...

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Bibliographic Details
Main Authors: Kitley, J, Elsone, L, George, J, Waters, P, Woodhall, M, Vincent, A, Jacob, A, Leite, M, Palace, J
Format: Journal article
Language:English
Published: 2013