Methotrexate is an alternative to azathioprine in neuromyelitis optica spectrum disorders with aquaporin-4 antibodies.
BACKGROUND: Neuromyelitis optica (NMO) is a severe autoimmune inflammatory disorder associated with considerable relapse-related disability. Immunosuppression is the mainstay of treatment but many patients do not tolerate first-line immunosuppressive agents, or experience ongoing relapses. OBJECTIV...
Hlavní autoři: | , , , , , , , , |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2013
|