Dual catalytic enantioselective desymmetrization of allene-tethered cyclohexanones
The construction of enantioenriched azabicyclo[3.3.1]nonan-6-one heterocycles via an enantioselective desymmetrization of allene-linked cyclohexanones, enabled through a dual catalytic system, that provides synchronous activation of the cyclohexanone with a chiral prolinamide and the allene with a c...
Main Authors: | Zhang, L, Yamazaki, K, Leitch, JA, Manzano, R, Atkinson, AM, Hamlin, TA, Dixon, DJ |
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Format: | Journal article |
Language: | English |
Published: |
Royal Society of Chemistry
2020
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