Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

Neisseria meningitidis is a major cause of bacterial septicemia and meningitis. Sequence variation of surface-exposed proteins and cross-reactivity of the serogroup B capsular polysaccharide with human tissues have hampered efforts to develop a successful vaccine. To overcome these obstacles, the en...

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Bibliographic Details
Main Authors: Pizza, M, Scarlato, V, Masignani, V, Giuliani, M, Aricò, B, Comanducci, M, Jennings, G, Baldi, L, Bartolini, E, Capecchi, B, Galeotti, C, Luzzi, E, Manetti, R, Marchetti, E, Mora, M, Nuti, S, Ratti, G, Santini, L, Savino, S, Scarselli, M, Storni, E, Zuo, P, Broeker, M, Hundt, E, Knapp, B
Format: Journal article
Language:English
Published: 2000

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