Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.
Neisseria meningitidis is a major cause of bacterial septicemia and meningitis. Sequence variation of surface-exposed proteins and cross-reactivity of the serogroup B capsular polysaccharide with human tissues have hampered efforts to develop a successful vaccine. To overcome these obstacles, the en...
Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2000
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