Characterization and differential nuclear localization of Nopp140 and a novel Nopp140-like protein in trypanosomes.

Trypanosomatids possess two homologues of Nopp140: a canonical Nopp140 and a Nopp140-like protein (TbNoLP) in which a GAR domain replaces the C-terminal SRP40 domain. Both are phosphorylated and coimmunoprecipitate with RNA polymerase I. Each paralogue has a distinct subnuclear localization, and dep...

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Bibliographic Details
Main Authors: Kelly, S, Singleton, W, Wickstead, B, Ersfeld, K, Gull, K
Format: Journal article
Language:English
Published: 2006