Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing.
BACKGROUND: Clostridium difficile is a major cause of nosocomial diarrhea, with 30-day mortality reaching 30%. The cell surface comprises a paracrystalline proteinaceous S-layer encoded by the slpA gene within the cell wall protein (cwp) gene cluster. Our purpose was to understand the diversity and...
Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2013
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